Bren Simon is supporting the USC Keck Medical Center to build a Sky Garden. Keck treats the sickest patients in the country and many for extended periods of time. Mrs. Simon sought to provide patients with a peaceful healing garden to escape the clinic setting – to smell the air, and sit amongst the flowers.

The Melvin and Bren Simon Charitable Foundation provides the National Democratic Institute (NDI) with funding to support organizations around the world that are helping create opportunities for women to get more involved in politics. The funding supports the Madeleine K. Albright Grant, as well as other NDI programs.

The Melvin and Bren Simon Charitable Foundation has provided a gift allowing the UCLA Division of Digestive Diseases to pursue diagnosis, treatment and research aimed at combating debilitating and deadly disorders affecting the gastrointestinal tract.

The Ride On Therapeutic Horsemanship annual fall fundraiser, hosted by Bren Simon at her home in Rancho de Caballos in Hidden Valley, raised significant funds to support the organization and its scholarship program.

Gleaners Food Bank is the largest charitable provider of food in Indiana. The Melvin and Bren Simon Foundation provides the organization with funding to support Gleaners’ mission of ensuring that no one in Indiana suffers from hunger and malnutrition.